Nicotine Upregulates the Level of Mcl-1 through STAT3 in H1299 Cells
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چکیده
منابع مشابه
Nicotine enhances the antiapoptotic function of Mcl-1 through phosphorylation.
Lung cancer has a strong etiologic association with cigarette smoking. Nicotine, a major component in tobacco smoke, functions as a survival agonist that inhibits apoptosis following various stresses. However, the mechanism of action remains elusive. Mcl-1, a major antiapoptotic protein of the Bcl2 family, is extensively expressed in both small cell and non-small cell lung cancer cells, suggest...
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ژورنال
عنوان ژورنال: Journal of Cancer
سال: 2020
ISSN: 1837-9664
DOI: 10.7150/jca.35453